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Engineered Zinc Finger Nuclease–Mediated Homologous Recombination of the Human Rhodopsin Gene

机译：工程锌指核酸酶介导的人类视紫红质基因的同源重组。

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摘要

Zinc finger nuclease–mediated homologous recombination is examined as a permanent genetic approach to treat retinitis pigmentosa.

机译：锌指核酸酶介导的同源重组被视为治疗色素性视网膜炎的永久遗传方法。

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Greenwald, David L.; Cashman, Siobhan M.; Kumar-Singh, Rajendra;
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年度 2010
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专利

1. Engineered zinc finger nuclease-mediated homologous recombination of the human rhodopsin gene. [J] . Greenwald DL, Cashman SM, Kumar Singh R Investigative ophthalmology & visual science . 2010,第12期

机译：人视紫红质基因的工程锌指核酸酶介导的同源重组。
2. Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination [J] . ColuccioA., MiselliF., LombardoA., Molecular therapy: the journal of the American Society of Gene Therapy . 2013,第9期

机译：锌指核酸酶介导的同源重组在人上皮干细胞中添加靶向基因
3. Sandwiched zinc-finger nucleases demonstrating higher homologous recombination rates than conventional zinc-finger nucleases in mammalian cells [J] . MoriT., MoriK., TobimatsuT., Bioorganic and Medicinal Chemistry Letters . 2014,第3期

机译：夹心的锌指核酸酶在哺乳动物细胞中的同源重组率高于常规锌指核酸酶
4. Mass Spectrometric O-Glycoproteome Analysis of Zinc-Finger Nuclease Glycoengineered Human Cell Lines ("SimpleCells") [C] . Sergey Y. Vakhrushev, Catharina Steentoft, Katrine T.-B. G. Schjoldager, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：锌 - 手指核酸甘油糖糖细胞系（“SimpleCells”）的质谱o-糖蛋白分析
5. Characterization of PfCRT F145I in Piperaquine-resistant Plasmodium falciparum Isolates from Cambodia Through Zinc-Finger Nuclease-mediated Gene Editing [D] . Shrestha, Biraj. 2019

机译：锌指核酸酶介导的基因编辑技术鉴定柬埔寨对哌拉喹的恶性疟原虫恶性疟原虫中PfCRT F145I的特性
6. Engineered Zinc Finger Nuclease–Mediated Homologous Recombination of the Human Rhodopsin Gene [O] . David L. Greenwald, Siobhan M. Cashman, Rajendra Kumar-Singh -1

机译：工程锌指核酸酶介导的人类视紫红质基因的同源重组。
7. Targeted gene addition in human epithelial stem cells by Zinc-finger nuclease-mediated homologous recombination [O] . Rio, Marcela del, Larcher, Fernando, Mavilio, Fulvio, 2013

机译：锌指核酸酶介导的同源重组在人上皮干细胞中添加靶向基因

Engineered Zinc Finger Nuclease–Mediated Homologous Recombination of the Human Rhodopsin Gene

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